In terms of inconsistent conclusions across all relevant randomized controlled trials (RCTs) and available meta-analyses, we aimed to use a meta-analysis and trial sequential analysis (TSA) to ...

For the majority of common human diseases, only a small fraction of the heritability can be attributed to known genetic variation. A widely held hypothesis is that the remaining heritability can be ...

The level of anticoagulation in response to a fixed-dose regimen of warfarin is difficult to predict during the initiation of therapy. We prospectively compared the effect of genotype-guided dosing ...