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  1. Elevated troponin and myocardial infarction in the intensive care unit ...

    Sep 28, 2005 · Cardiac troponin is specific to the myocardium, and levels in the serum rise 3–4 hours after the occurrence of cardiac symptoms in patients with acute myocardial infarction (MI) [1]. …

  2. A high mean arterial pressure target is associated with improved ...

    Introduction The effect of mean arterial pressure titration to a higher level on microcirculation in septic shock patients with previous hypertension remains unknown. Our goal is to assess the effect of …

  3. New-onset atrial fibrillation and associated outcomes and resource use ...

    Background New-onset atrial fibrillation (NOAF) is commonly encountered in critically ill adults. Evidence evaluating the association between NOAF and patient-important outcomes in this population is …

  4. Heterogeneity of treatment effect: the case for individualising oxygen ...

    Oxygen therapy is ubiquitous in critical illness but oxygenation targets to guide therapy remain controversial despite several large randomised controlled trials (RCTs). Findings from RCTs …

  5. Mar 13, 2009 · Methods Patients were interviewed within 1 hour of first physician evaluation, in the emergency department or acute care setting, with dyspnea assessed by the patient using both a five …

  6. The effects of blood cell salvage on transfusion requirements after ...

    Background Veno-venous extracorporeal membrane oxygenation (VV-ECMO) is a supportive therapy for acute respiratory failure with increased risk of packed red blood cells (PRBC) transfusion. Blood …

  7. Rationale for sequential extracorporeal therapy (SET) in sepsis ...

    Abstract Sepsis and septic shock remain drivers for morbidity and mortality in critical illness. The clinical picture of patients presenting with these syndromes evolves rapidly and may be characterised by: (a) …

  8. Impact of syndromic molecular diagnostics on antimicrobial adequacy …

    Pneumonia is a leading cause of ICU admission and mortality, requiring prompt and adequate antimicrobial therapy to improve outcomes. Conventional cultures are slow and often insensitive, …

  9. A multicenter, prospective validation study of the Japanese Association ...

    Introduction To validate the Japanese Association for Acute Medicine (JAAM) disseminated intravascular coagulation (DIC) scoring system in patients with severe sepsis, we conducted a …

  10. Whether the display of regional ventilation distribution during a Spontaneous Breathing Trial (SBT) could help at pre-dicting early and successful liberation from MV.