Spatial transcriptomics, or spatially resolved transcriptomics, is a method that captures positional context of transcriptional activity within intact tissue. [1]

Spatial transcriptomics (ST) is a significant advancement in life science research, enabling transcriptome analysis to transition from traditional bulk and single-cell levels to spatial location …

This technology offers a novel perspective for understanding the spatial variations and distributions of gene expression. With the emergence of spatial transcriptomics, our ability to understand drug …

Jan 20, 2025 · Spatial transcriptomics technology enables the mapping of gene expression within tissues, allowing researchers to visualize the spatial distribution of RNA molecules and gain insights …

Jan 6, 2021 · Nature Methods has crowned spatially resolved transcriptomics Method of the Year 2020.

What is spatial transcriptomics? Spatial transcriptomics measures both the expression of your genes of interest and where in the tissue they’re expressed. By doing so, it enables huge leaps in …

Jun 1, 2024 · Spatial transcriptomics has rapidly evolved from its conceptual beginnings into a powerful tool that offers unprecedented insights into the spatial distribution of gene expression within …

What is spatial transcriptomics? The goal of spatial transcriptomics is to measure gene expression (i.e. quantify mRNA transcripts) in the spatial context of a tissue sample. Genes, cells, and cell …

5 days ago · /PRNewswire/ -- Stellaromics today launched Pyxa™, the first commercially available platform to deliver multiplexed 3D spatial transcriptomics in intact tissue...

6 days ago · Abstract Spatial transcriptomics (ST) offers unprecedented opportunities to decode the spatial organization of gene expression, yet the inherent noise and complexity of ST data pose …

In this review, we introduce the technical advancement of spatial transcriptomics over the years and demonstrate the capabilities of spatial transcriptomics in a variety of biological investigations.

2 days ago · The field of spatial transcriptomics (ST) has witnessed a transformative surge over recent years, profoundly reshaping our understanding of gene expression patterns in the spatial …

Mar 10, 2022 · To study the spatial patterns of gene expression, many different spatial transcriptomics methods, which produce spatially localized quantification of messenger RNA (mRNA) …

1 day ago · One of the key challenges in spatial transcriptomics data analysis is the lack of sufficient data to train the models. To address this shortcoming, multiple generative models have been …

15 hours ago · In a groundbreaking leap for spatial transcriptomics, researchers have introduced an innovative method dubbed volumetric DNA microscopy, offering an unprecedented window into the …

Spatial transcriptomic technology is used to parse RNA-seq data at the spatial level, which can simultaneously obtain the spatial context and transcriptional pattern of cells to improve our …

Jun 27, 2022 · Since spatial information is preserved by studying intact tissue, these methods have been referred to as spatially-resolved transcriptomics, or simply ‘spatial transcriptomics’.

Jun 8, 2018 · Since Becker and his team first started using spatial transcriptomics in their research work, just about four years ago, there have been significant technological advances in terms of the …

May 8, 2024 · This Review provides an overview of current and emerging spatial transcriptomic methods, their applications and remaining challenges for the field.

Jan 6, 2025 · Spatial transcriptomics (ST) represents a revolutionary approach in molecular biology, providing unprecedented insights into the spatial organization of gene expression within tissues.

Sep 19, 2025 · Spatial transcriptomics (ST) enables the in situ mapping of gene expression, revolutionizing our ability to study tissue organization and cellular interactions.

The key difference between imaging-based and sequencing-based spatial transcriptomics technologies lies in their distinct approaches to determine the spatial localization and abundance of …

Feb 17, 2026 · CubaseBio secures €5.9 million to advance 3D spatial transcriptomics powered by DNA microscopy and RNA sequencing, enabling scalable volumetric gene expression mapping for …

Dec 31, 2025 · Spatial transcriptomics (ST) has emerged as a transformative technology in modern biology, enabling researchers to map gene expression patterns while preserving crucial spatial …

Sep 1, 2023 · In this review, we introduce recent progresses and challenges on SRT from the perspectives of technologies and bioinformatic tools, as well as the representative SRT applications.

2 days ago · Background Xylem development is a dynamic, continuous process fundamental to secondary growth in woody plants and to biomass accumulation on earth. While single-cell RNA …

In this review, we present the fundamental principles of spatial transcriptomic methods, discuss the challenges in data analysis, provide insights into experimental considerations, offer information about …

Technological advances in spatial transcriptomics Spatial omics technologies are undergoing a profound transformation, shifting from low-throughput localization to high-throughput panoramic …

Recent advances in transcriptome profiling preserve the in situ spatial context of RNA molecules and together comprise a group of techniques known as “spatial transcriptomics,” enabling localization …

In this paper, we review key enabling spatial transcriptomic technologies and their applications as well as the perspective of the techniques and new emerging technologies that are developed to address …